Responsible Breeding

DNA testing.

Understanding what a cat may carry—even when that cat appears completely healthy—is an important part of thoughtful breeding.

Some hereditary conditions can be passed silently from parent to kitten because a carrier may show no signs of disease. DNA screening helps breeders identify these genetic risks, make informed breeding decisions, and reduce the likelihood of producing affected kittens.

Comprehensive genetic health screening

Both parents were tested.

Basepaws

Clear

43 of 43 genetic health conditions clear

Wisdom Panel

Clear

49 of 49 genetic health conditions clear

Both parents: zero disease-carrier, at-risk, or high-risk genetic health findings.

What was tested

We take the health of our kittens very seriously. House of Neva uses the world’s most comprehensive cat DNA test. Both parents were screened for over 45 health genetic conditions. All are

Basepaws (43)

  • Fibrodysplasia Ossificans
  • Myotonia Congenita
  • Ehlers-Danlos Syndrome
  • Vitamin D-deficiency rickets, type IA
  • Vitamin D-deficiency rickets, type IB
  • Hypokalemic Periodic Paralysis
  • Progressive Retinal Atrophy (AIPL1-related)
  • Late-Onset Photoreceptor Degeneration (rdAc)
  • Progressive Retinal Atrophy (KIF3B-related)
  • Glaucoma
  • Mucopolysaccharidosis VI
  • Wilson's Disease
  • Neuronal Ceroid Lipofuscinosis
  • Dihydropyrimidinuria
  • Gangliosidosis, type GM1
  • Gangliosidosis, type GM2 (variant AB)
  • Mucopolysaccharidosis VII
  • Gangliosidosis, type GM2 (variant 0)
  • Porphyria, acute intermittent (AIP)
  • Mucopolysaccharidosis I
  • Hyperlipoproteinaemia
  • Alpha-mannosidosis
  • Niemann-Pick disease, type C1
  • Niemann-Pick disease, type C2
  • Pyruvate Kinase Deficiency
  • Niemann-Pick disease, type A
  • Porphyria, congenital erythropoietic (CEP)
  • Methemoglobinemia
  • Factor XII Deficiency
  • Haemophilia B
  • Glanzmann Thrombasthenia
  • Congenital Adrenal Hyperplasia
  • Hypogonadotropic Hypogonadism
  • Hypothyroidism
  • Autoimmune Lymphoproliferative Syndrome
  • Leukocyte Adhesion Deficiency
  • Primary Hyperoxaluria
  • Polycystic Kidney Disease
  • Cystinuria, type IA
  • Cystinuria, type B
  • Epidermolysis Bullosa Simplex
  • Inflammatory Linear Verrucous Epidermal Nevus
  • Hypertrophic Cardiomyopathy

Wisdom Panel (49)

  • Acute Intermittent Porphyria (Variant 1)
  • Acute Intermittent Porphyria (Variant 2)
  • Acute Intermittent Porphyria (Variant 3)
  • Acute Intermittent Porphyria (Variant 4)
  • Acute Intermittent Porphyria (Variant 5)
  • Autoimmune Lymphoproliferative Syndrome
  • Burmese Head Defect
  • Chediak-Higashi Syndrome
  • Congenital Adrenal Hyperplasia
  • Congenital Erythropoietic Porphyria
  • Congenital Myasthenic Syndrome
  • Cystinuria Type 1A
  • Cystinuria Type B (Variant 1)
  • Cystinuria Type B (Variant 2)
  • Cystinuria Type B (Variant 3)
  • Dihydropyrimidinase Deficiency
  • Earfold and Osteochondrodysplasia
  • Factor XII Deficiency (Variant 1)
  • Factor XII Deficiency (Variant 2)
  • Familial Episodic Hypokalemic Polymyopathy
  • Glutaric Aciduria Type II
  • Glycogen Storage Disease
  • GM1 Gangliosidosis
  • GM2 Gangliosidosis
  • GM2 Gangliosidosis Type II (Domestic Shorthair)
  • GM2 Gangliosidosis Type II (Japanese Domestic)
  • GM2 Gangliosidosis Type II (Burmese)
  • Hemophilia B (Variant 1)
  • Hemophilia B (Variant 2)
  • Hyperoxaluria Type II
  • Hypertrophic Cardiomyopathy (Maine Coon)
  • Hypertrophic Cardiomyopathy (Ragdoll)
  • Hypotrichosis
  • Lipoprotein Lipase Deficiency
  • MDR1 Medication Sensitivity
  • Mucopolysaccharidosis Type I
  • Mucopolysaccharidosis Type VI
  • Mucopolysaccharidosis Type VI Modifier
  • Mucopolysaccharidosis Type VII (Variant 1)
  • Mucopolysaccharidosis Type VII (Variant 2)
  • Myotonia Congenita
  • Polycystic Kidney Disease (PKD)
  • Progressive Retinal Atrophy (Abyssinian)
  • Progressive Retinal Atrophy (Bengal)
  • Progressive Retinal Atrophy (Persian)
  • Pyruvate Kinase Deficiency
  • Sphingomyelinosis (Variant 1)
  • Sphingomyelinosis (Variant 2)
  • Vitamin D-Dependent Rickets

What the results tell us

At The House of Neva, all parents have completed a comprehensive feline DNA screening through two established genetic testing companies. Parents were tested through Basepaws for 43 genetic health conditions and received 43 clear results, and Wisdom Panel for 49 genetic health conditions and received 49 clear results.

Both parents' DNA profiles also identified the expected longhair and colorpoint traits associated with Neva Masquerade cats.

All litters are tested negative for feline leukemia virus (FeLV).

DNA testing cannot screen for every possible health condition or guarantee a kitten's future health. However, it is an important part of responsible breeding when combined with attentive veterinary care and appropriate health screening.

Kittens are vulnerable to changes and stress

Kittens can be sensitive to change and may become stressed easily, so their new environment matters a great deal. A calm, quiet, and welcoming home can help a kitten adjust more comfortably. Providing a consistent routine, gentle handling, and a safe space to retreat to can support a smoother transition and help the kitten feel secure as it settles in.

Kittens can go downhill quickly, so monitoring their health and environment is important. Contact your veterinarian promptly if you notice a sudden change in appetite, energy, behavior, breathing, or litter-box habits.